RISK FACTORS FOR STAPHYLOCOCCAL TOXIC-SHOCK SYNDROME

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Abstract
Fifty-two cases of toxic-shock syndrome that occurred in January 1, 1976 through August 31, 1980, were reported to the Utah State Health Department between February 1 and August 31, 1980. The annual attack rate for Utah based on a six-month surveillance period was 14.4 per 100,000 women ages 12–49 years. All cases were in women who had onset of illness within two days of menses. Potential risk factors were investigated with a case-control study utilizing 29 women hospitalized with toxic-shock syndrome and 91 neighbor hood female controls. Nine of the 29 (31%) women reported recurrences of similar illness. Use of tampons (p = 0.012) and use of a single brand of tampon—Rely—during the month of illness (p p <0.05, RR = 0.277). This epidemiologic investigation of toxic- shock syndrome in menstrual-age women has identified tampons generally and a single brand specifically as significant risk factors in acquiring toxicshock syndrome.

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