Indigenous bacteria that influence the number of Salmonella typhimurium in the spleen of intravenously challenged mice

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Abstract
Intravenous inoculation of conventional mice with 6 out of 13 bacterial strains indigenous to the mouse gastrointestinal tract led to reduced numbers of Salmonella typhimurium in the spleen following intravenous challenge with the pathogen. Gnotobiotic mice harbouring an Enterococcus in their gastrointestinal tract did not have Salmonella in the spleen following intravenous challenge. Some germfree mice or gnotobiotic mice associated with a Lactobacillus strain, in contrast, had Salmonella in the spleen following challenge.

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