Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice

This publication has 33 references indexed in Scilit:

• B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil
  The Journal of Experimental Medicine, 2005
• Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice
  Oncogene, 2005
• DNA deamination in immunity
  Immunological Reviews, 2005
• Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts
  Carcinogenesis: Integrative Cancer Research, 2004
• Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas
  Oncogene, 2003
• RNA Editing Enzyme APOBEC1 and Some of Its Homologs Can Act as DNA Mutators
  Molecular Cell, 2002
• hUNG2 Is the Major Repair Enzyme for Removal of Uracil from U:A Matches, U:G Mismatches, and U in Single-stranded DNA, with hSMUG1 as a Broad Specificity Backup
  Journal of Biological Chemistry, 2002
• The Structure and Function of γс-Dependent Cytokines and Receptors: Regulation of T Lymphocyte Development and Homeostasis
  Critical Reviews in Immunology, 1998
• Tumor Necrosis Factor-α (TNF-α) and Interleukin-6 (IL-6) in B-Lymphocyte Function
  Methods, 1997
• Regulation of interleukin-2 and interleukin-6 production from T-cells: Involvement of interleukin-1 β and transforming growth factor-β
  Cellular Immunology, 1990