Abstract
The relationships between the size and sex composition of the litter and puberty in femal mice were investigated. Both factors significantly affected the age of 1st vaginal estrus; litter size accounted for 22% of the total variation in age at puberty and litter sex composition for 8%. When no males or only 1 male was present in litters of 10 young the females matured significantly earlier than when 2 or more males were present (pheromonal effect).

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