Über das Vorkommen von Trimethyl-acetonyl-ammoniumhydroxyd im menschlichen Harn

Abstract
Small amounts of trimethyl-acetonly-ammonium hydroxide are found regularly in human urine. It may be formed from endogenous carnitine via its 3-dehydroderivative(4-trimethylammonio-3-oxobutyric acid hydroxide). This degradation pathway would correspond to that in Pseudomonads. The detected amount of trimethyl-acetonly-ammonium hydroxide is of an order of magnitude which would correspond to the turnover rate of the endogenous carnitine, if it is assumed that the latter is produced non-enzymatically from the intermediate 3-dehydrocarnltine as in Pseudomonads.