QRS Amplitudes, QTc Intervals and ECG Abnormalities in Pheochromocytoma Patients before, during and after Treatment

Publisher Website
Google Scholar
Abstract
QRS amplitudes (S1 + R5), Minnesota Code ECG abnormalities and QTc intervals were analyzed in ECGs from 31 pheochromocytoma patients on admission to hospital, after 17±7.2 (SD) days of preoperative phenoxybenzamine therapy in a dosage of 148± 45.0 (SD) mg/day and after a mean postoperative follow‐up of 6 years. QRS voltage decreased significantly from 3.37± 1.48 on admission, to 2.26±0.69 mV at postoperative follow‐up (pc interval was 0.44±0.04 s on admission and 0.41±0.02 s at follow‐up (p<0.01). No significant differences were observed during treatment with phenoxybenzamine. Pathological ECGs are common findings in patients with pheochromocytoma and significant improvements occur after surgery. Significant effects of phenoxybenzamine therapy were only found in patients with sustained hypertension.