THE CLINICAL VALUE OF VITAMIN K
- 28 September 1940
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 115 (13) , 1082-1087
- https://doi.org/10.1001/jama.1940.02810390022005
Abstract
As vitamin K has only recently been discovered, and synthetic substances with vitamin K activity are at the present time receiving intensive study, our knowledge as to the clinical value of this vitamin is as yet very limited. Although its effect on the hemorrhagic diathesis in chicks on a vitamin K deficient diet has been fairly well worked out, its therapeutic use with patients is largely an unsolved problem. A few disorders with K deficiency are now well recognized; its relationship to a number of others seems probable, and it is possible that it may be of some importance in certain hemorrhagic conditions which have received little or no study up to the present time. Largely on empirical grounds it has been stated that this vitamin is of no value in a number of conditions in which free bleeding may occur. Clinical studies have been advanced to some extent byKeywords
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