EXPERIMENTAL PARACOCCIDIOIDOMYCOSIS - CRANIAL AND NASAL LOCALIZATION IN MICE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 59  (4) , 339-344
Abstract
An experimental mouse model for paracoccidioidomycosis (South American blastomycosis) is described. When distribution of cranial lesions following i.v. injection was investigated, invasion of the nasal mucosa with subsequent discharge of budding Paracoccidioides brasiliensis cells into the nasal cavity was noted. The possible significance of this finding in terms of the processes associated with naturally occurring paracoccidioidomycosis is discussed.