Selective Alkylation of Ketones with a Bulky Aluminum Reagent-the THF-TBSOTf System
- 1 April 1997
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1997 (4) , 357-358
- https://doi.org/10.1055/s-1997-792
Abstract
Various ketones can be alkylated with tetrahydrofuran (THF) to provide α-siloxybutylated ketones in the presence of a bulky aluminum reagent, lithium diisopropylamide (LDA), and t-butyldimethylsilyl triflate (TBSOTf).Keywords
This publication has 0 references indexed in Scilit: