Electron Microscopic Observations on a “C”-Type Virus in Cell Cultures Derived From a Tumor-Bearing Viper2

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Abstract
Electron microscopic studies on tissues and cell cultures derived from a tumor-bearing Russell's viper revealed a “C”-type, budding virus associated with the spleen cell line in late passage. Virions have not been observed in the primary tissues, the edematous myxofibroma, or other culture lines to date. The virions were approximately 108 mμ, membrane bound, and possessed a dense nucleoid. These observations support the extension of the range of this family of presumably RNA-containing viruses into the cold-blooded vertebrate group.

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