Brachial-ankle pulse wave velocity and symptomatic cerebral infarction in patients with type 2 diabetes: a cross-sectional study
Open Access
- 28 August 2003
- journal article
- research article
- Published by Springer Nature in Cardiovascular Diabetology
- Vol. 2 (1) , 10
- https://doi.org/10.1186/1475-2840-2-10
Abstract
Recently a new automatic device that measures brachial-ankle pulse wave velocity using an oscillometric method has been developed. However, the practical significance of brachial-ankle pulse wave velocity measurement remains uncertain. The purpose of this study was to examine the association between brachial-ankle pulse wave velocity and symptomatic cerebral infarction in patients with type 2 diabetes. One thousand sixty six patients with type 2 diabetes were studied cross-sectionally. Measurements of brachial-ankle pulse wave velocity were made using the automatic device. Logistic regression analysis was used to calculate the odds ratio for cerebral infarction. The presence of symptomatic cerebral infarction was confirmed in 86 patients. In these patients brachial-ankle pulse wave velocity was found to be significantly higher than in patients without cerebral infarction (18.94 ± 4.95 versus 16.46 ± 3.62 m/s, p < 0.01). The association between brachial-ankle pulse wave velocity and cerebral infarction remained significant after adjustment for traditional risk factors. There was an increasing odds ratio for each tertile of brachial-ankle pulse wave velocity, from the second tertile (odds ratio, 2.28; 95% confidence interval, 1.05 to 4.94), to the third (odds ratio, 2.53; 95% confidence interval, 1.09 to 5.86). Overall, we conclude that an increase in brachial-ankle pulse wave velocity is associated with symptomatic cerebral infarction in patients with type 2 diabetes.Keywords
This publication has 13 references indexed in Scilit:
- Influences of age and gender on results of noninvasive brachial–ankle pulse wave velocity measurement—a survey of 12 517 subjectsAtherosclerosis, 2003
- Validity, Reproducibility, and Clinical Significance of Noninvasive Brachial-Ankle Pulse Wave Velocity Measurement.Hypertension Research, 2002
- Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Subjects >70 Years of AgeArteriosclerosis, Thrombosis, and Vascular Biology, 2001
- Aortic Stiffness Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Hypertensive PatientsHypertension, 2001
- Association Between Arterial Stiffness and AtherosclerosisStroke, 2001
- Clinical Usefulness of Measuring Pulse Wave Velocity in Predicting Cerebrovascular Disease. Evaluation from a Cross-Sectional and Longitudinal Follow-up Study.Journal of Nippon Medical School, 2001
- Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 diabetes. Vessel wall properties in type 2 diabetes.Diabetes Care, 1999
- Impact of Aortic Stiffness on Survival in End-Stage Renal DiseaseCirculation, 1999
- Aortic Distensibility in Patients with Cerebrovascular DiseaseClinical Science, 1995
- Special report from the National Institute of Neurological Disorders and Stroke. Classification of cerebrovascular diseases III.Stroke, 1990