Purification of γ-Benzyl and γ-Methyl L-Glutamate N-Carboxyanhydrides by Rephosgenation
- 1 December 1992
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 22 (22) , 3257-3262
- https://doi.org/10.1080/00397919208021140
Abstract
Rephosgenation of N-carboxyanhydrides of γ-benzyl and y-methyl L-glutamates, vs multiple recrystallizations, is a very efficient method for obtaining highly purified N-carboxyanhydrides, from which very high MW (0.98-1.5 × 106 Daltons) polymers can be derived.Keywords
This publication has 9 references indexed in Scilit:
- The use of triphosgene in preparation of N-carboxy .alpha.-amino acid anhydridesThe Journal of Organic Chemistry, 1992
- The preparation of N-carboxyanhydrides of α-amino acids using bis(trichloromethyl)carbonateTetrahedron Letters, 1988
- On the Dissolution of Poly(γ-methyl L-glutamate) in a Mixed Solvent of Benzene and MethanolPolymer Journal, 1980
- A procedure for the facile syntheis of amino‐acid N‐carboxyanhydridesBiopolymers, 1976
- Polypeptides. IV. The Molecular Weight, Configuration and Association of Poly-γ-benzyl-L-glutamate in Various SolventsJournal of the American Chemical Society, 1956
- Polypeptides. III. The Synthesis of High Molecular Weight Poly-γ-benzyl-L-glutamates1Journal of the American Chemical Society, 1956
- 632. Synthetic polypeptides. Part II. Polyglutamic acidJournal of the Chemical Society, 1950
- Über die Isomerie der Carbäthoxyl‐glycyl glycinesterEuropean Journal of Inorganic Chemistry, 1907
- Ueber die Glycin‐carbonsäureEuropean Journal of Inorganic Chemistry, 1906