Pathogenesis of Experimental Hypertension Produced by Carotid Sinus Area Constriction in Dogs

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Abstract
Bilateral constriction of the carotid sinus area, the immediate arterial branches of the sinus, or (perhaps) the vertebral arteries, and bilateral resection of the carotid sinus produces a significant, persistent hypertension in dogs, the highest levels occurring in the carotid sinus area constricted dogs. Pathogenesis is still unsettled.