Apoptosis: Programmed Cell Death
Open Access
- 1 July 1998
- journal article
- review article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 133 (7) , 773-775
- https://doi.org/10.1001/archsurg.133.7.773
Abstract
Urrently there is much interest and excitement in the understanding of how cells un- dergo the process of apoptosis or programmed cell death. Understanding how, why, and when cells are instructed to die may provide insight into the aging process, au- toimmune syndromes, degenerative diseases, and malignant transformation. This re- view focuses on the development of apoptosis and describes the process of programmed cell death, some of the factors that incite or prevent its occurrence, and finally some of the diseases in which it may play a role. The hope is that in the not too distant future we may be able to modify or thwart the apoptotic process for therapeutic benefit.Keywords
This publication has 1 reference indexed in Scilit:
- The extracellular matrix as a cell survival factor.Molecular Biology of the Cell, 1993