Replacement of the Negative Phosphodiester Linkages of DNA by PositiveS-Methylthiourea Linkers: A Novel Approach to Putative Antisense Agents
- 18 June 1998
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 120 (26) , 6619-6620
- https://doi.org/10.1021/ja980629q
Abstract
No abstract availableThis publication has 17 references indexed in Scilit:
- ANTISENSE OLIGONUCLEOTIDES AS THERAPEUTIC AGENTSPharmacological Research, 1997
- Mixed-Backbone Oligonucleotides Containing Phosphorothioate and Methylphosphonate Linkages as Second Generation Antisense OligonucleotideNucleosides and Nucleotides, 1997
- Fidelity of Binding of the Guanidinium Nucleic Acid (DNG) d(Tg)4-T-azido with Short Strand DNA Oligomers (A5G3A5, GA4G3A4G, G2A3G3A3G2, G2A2G5A2G2). A Kinetic and Thermodynamic StudyBiochemistry, 1997
- Backbone modifications for antisense oligonucleotidesPublished by Walter de Gruyter GmbH ,1997
- Association of Short-Strand DNA Oligomers with Guanidinium-Linked Nucleosides. A Kinetic and Thermodynamic StudyJournal of the American Chemical Society, 1996
- Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?Science, 1993
- Comparative evaluation of seven oligonucleotide analogs as potential antisense agentsJournal of Medicinal Chemistry, 1993
- Therapeutic Applications of OligonucleotidesAnnual Review of Pharmacology and Toxicology, 1992
- Intramolecular energy transfer in the inverted regionJournal of the American Chemical Society, 1992
- Cationic oligonucleotidesJournal of the American Chemical Society, 1988