Effect of Motor Cortex Ablations on Reflex Myoclonus in the Monkey

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Abstract
Sharply limited ablation of the arm or leg area of the precentral motor cortex in the macaque produces a complete or partial depression of the reflex myoclonic responses of the affected extremities as elicited after subconvulsant Metrazol dosage. This occurs in chronic. as well as acute prepns. When responses are present, there is a predominance of extensor muscle activity with marked diminution of finger or toe-flexor responses. A similar pattern is observed when generalized seizures are elicited by repetitive acoustic stimulation.

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