The resolution and absolute configuration of the isomeric 2-dimethylaminocyclohexanols and their derivatives

Publisher Website
Google Scholar
Abstract
The preparation of the enantiomers of cis- and trans-2-dimethylaminocyclohexylacetate methiodide (potential substrates for the enzyme acetylcholinesterase) is reported. The absolute configuration of the cis-enantiomers has been shown from their relationship with compounds of known configuration. The configuration of the trans-enantiomers is inferred from o.r.d. spectral studies.