Time Sequence of 3',5'-Cyclic AMP Accumulation and Ultrastructural Changes in Dog Thyroid Slices after Acute Stimulation by TSH

Abstract
CAMP accumulation and pseudopod formation have been studied in dog thyroid slices stimulated by thyrotropin. It is shown that the kinetics and concentration effect relationship support the validity of Sutherland's model of hormone action through cAMP for thyrotropin and thyroid secretion. 1 Work done with the aid of grants no. 20013 and 20472 of the FRSM and under Contract of the Ministère de la Politique Scientifique within the framework of the Association Euratom - University of Brussels - University of Pisa.

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