Dengue Type 3 Virus Isolated from an Antiguan Patient during the 1963–64 Caribbean Epidemic *
- 1 July 1969
- journal article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 18 (4) , 584-587
- https://doi.org/10.4269/ajtmh.1969.18.584
Abstract
A strain of dengue type 3 virus was isolated from the blood of an Antiguan patient in cell cultures of African green-monkey kidney during studies on a dengue outbreak that occurred in the Caribbean region in 1963 and 1964. The virus was adapted to mice by blind intracerebral passage. Illness appeared in mice at the 11th mouse-brain passage. Four other agents, presumed to be dengue type 3 strains, were isolated from Antiguan patients. Serologic studies on paired serum samples from patients of five Caribbean territories showed that the outbreak was due to a group B arbovirus.Keywords
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