Trial of Chloramphenicol for Meningitis in Northern Savanna of Africa
- 18 August 1973
- Vol. 3 (5876) , 379-381
- https://doi.org/10.1136/bmj.3.5876.379
Abstract
In a controlled trial chloramphenicol proved as effective and much cheaper than penicillin for the treatment of group A meningococcal meningitis in Zaria, Nigeria. A short course of five days cured most patients. Adults and older children were soon able to take chloramphenicol by mouth, which reduced the cost and simplified treatment. It is suggested that chloramphenicol is a suitable alternative to sulphonamides for the treatment of meningococcal meningitis in those parts of Africa where the organism is sulphonamide-resistant.Keywords
This publication has 10 references indexed in Scilit:
- Efficacy of intramuscular chloramphenicol in treatment of H. influenzae meningitisThe Journal of Pediatrics, 1972
- COUNTER-CURRENT IMMUNOELECTROPHORESIS IN THE DIAGNOSIS OF MENINGOCOCCAL INFECTIONSThe Lancet, 1971
- Evaluation of Chloramphenicol Acid Succinate Therapy of Induced Typhoid Fever and Rocky Mountain Spotted FeverNew England Journal of Medicine, 1970
- Statewide Study of Chloramphenicol Therapy and Fatal Aplastic AnemiaJAMA, 1969
- General review of the treatment of meningitis.1969
- [Biological and clinical data concerning the reaction of Neisseria meningitides A to several sulfonamides and antibiotics: observations at Fort-Lamy (Chad) during a seasonal outbreak of cerebrospinal meningitis].1969
- Sulfa-drug resistance and serologic studies of a meningococcal meningitis epidemic.1969
- Changing Susceptibility of Meningococci to Antimicrobial AgentsNew England Journal of Medicine, 1965
- Therapeutic range of chloramphenicol in purulent meningitis.1955
- Treatment of meningitis with chloromycetin palmitate; results of therapy in twenty-three cases.1953