Abstract
Tests on adults of the migratory grasshopper, Melanoplus bilituratus (Wlk.), showed carbaryl (1-naphthyl N-methylcarbamate) to have a very marked negative temperature coefficient of toxicity. This was believed to be due to a rapid increase in the rate of detoxification at higher temperatures. The marked synergistic effect of piperonyl butoxide, believed to act by blocking the detoxification process, appeared to confirm this.

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