Symmetry and the energy landscapes of biomolecules
- 10 December 1996
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 93 (25) , 14249-14255
- https://doi.org/10.1073/pnas.93.25.14249
Abstract
The role of symmetry in the folding of proteins is discussed using energy landscape theory. An analytical argument shows it is much easier to find sequences with funneled energy landscape capable of fast folding if the structure is symmetric. The analogy with phase transitions of small clusters with magic numbers is discussed.Keywords
This publication has 38 references indexed in Scilit:
- Allosteric proteins and cellular control systemsPublished by Elsevier ,2009
- Magic Numbers in Protein StructuresPhysical Review Letters, 1996
- From Topographies to Dynamics on Multidimensional Potential Energy Surfaces of Atomic ClustersScience, 1996
- Why are the same protein folds used to perform different functions?FEBS Letters, 1993
- General architecture of the α-helical globuleJournal of Molecular Biology, 1988
- Deduction and systematic classification of spatial motifs of the antiparallel β structure in globular proteinsActa Crystallographica Section A Foundations of Crystallography, 1987
- The concept of frustration in spin glassesJournal of the Less Common Metals, 1978
- On the nature of allosteric transitions: A plausible modelJournal of Molecular Biology, 1965
- Physical Principles in the Construction of Regular VirusesCold Spring Harbor Symposia on Quantitative Biology, 1962
- Über quantenmechanische Resonanzanziehung und über das Problem der ImmunitätsreaktionenThe European Physical Journal A, 1939