Organische Phosphorverbindungen 40. Methoden zur Herstellung von Pentamethylen‐1,5‐bis‐(dihydroxyphosphonylmethyl‐phosphinsäure) [1]

Publisher Website
Google Scholar
Abstract
Alkyl‐pentamethylene‐1,5‐bis‐(dialkyloxyphosphonylmethyl‐phosphinates) (VII) are formed in high yield by heating alkyl pentamethylene‐1,5‐diphosphonites, (RO)2P(CH2)5P(OR)2, with alkyl chloromethylphosphonates, ClCH2P(O)(OR)2, at 170° for several hours until evolution of alkyl halides ceases. Hydrolysis to the corresponding acid (VIII) is effected by refluxing with conc. HCl for 40 h.The synthesis and properties of some other 1,5‐diphosphorus‐substituted pentanes, i.e., H2P(CH2)5PH2, Cl2P(CH2)5PCl2, (Et2N)2P(CH2)5P(NEt2)2, (EtO) (HO)P(CH2)5P(OH)(OEt), and (HO)2P(CH2)5P(OH)2, are also reported.