Evaluation of available IgE‐binding epitope data and its utility in bioinformatics
- 30 June 2006
- journal article
- review article
- Published by Wiley in Molecular Nutrition & Food Research
- Vol. 50 (7) , 638-644
- https://doi.org/10.1002/mnfr.200500276
Abstract
This paper reviews the role played by IgE‐binding epitopes in eliciting clinical symptoms, the types of IgE‐binding epitopes in allergenic proteins, the methods used to identify IgE‐binding epitopes, and the availability of IgE‐binding epitopes in allergenic sources. Finally, bioinformatics methods to assess protein allergenicity using knowledge of IgE‐binding epitopes are discussed.Keywords
This publication has 46 references indexed in Scilit:
- Roles of major oligosaccharides on Cry j 1 in human immunoglobulin E and T cell responsesClinical and Experimental Allergy, 2004
- Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structureBiochemical Journal, 2003
- Identification of Sequential IgE-Binding Epitopes on Bovine αs2-Casein in Cow’s Milk Allergic PatientsInternational Archives of Allergy and Immunology, 2002
- The Major Conformational IgE-binding Epitopes of Hevein (Hev b6.02) Are Identified by a Novel Chimera-based Allergen Epitope Mapping StrategyPublished by Elsevier ,2002
- Bioinformatic Methods for Identifying Known or Potential Allergens in the Safety Assessment of Genetically Modified CropsComments on Toxicology, 2002
- Hydrogen Exchange Nuclear Magnetic Resonance Spectroscopy Mapping of Antibody Epitopes on the House Dust Mite Allergen Der p 2Journal of Biological Chemistry, 2001
- A Soybean G2 Glycinin AllergenInternational Archives of Allergy and Immunology, 2000
- Assessment of the allergenic potential of foods derived from genetically engineered crop plants*Critical Reviews in Food Science and Nutrition, 1996
- Type I allergic reactions to plant-derived food: A consequence of primary sensitization to pollen allergens*Journal of Allergy and Clinical Immunology, 1996
- Prediction of protein antigenic determinants from amino acid sequences.Proceedings of the National Academy of Sciences, 1981