Histological changes in the vaginal connective tissue of patients with and without uterine prolapse

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Abstract
The histological structure of the vaginal fascia was studied in two groups of patients: 10 consecutive women having a vaginal repair for uterine prolapse or descent and 10 consecutive women having an abdominal hysterectomy for fibroids. Abnormal histological changes were found in 7 out of 10 patients with uterine descent as compared to 2 out of 10 controls (P < 0.05). This suggests a correlation between histological changes in vaginal connective tissue and pelvic laxity.