Bone Resorption Inhibitors from Hop Extract
- 1 January 1997
- journal article
- Published by Oxford University Press (OUP) in Bioscience, Biotechnology, and Biochemistry
- Vol. 61 (1) , 158-159
- https://doi.org/10.1271/bbb.61.158
Abstract
We searched hop extract for active component(s) that inhibited bone resorption in the pit formation assay, and isolated xanthohumol and humulone as active ingredients. Especially humulone had extraordinarily strong inhibitory activity and the IC50 (concentration of 50% inhibition) value was 5.9 x 10(-9)M.Keywords
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