EFFECT OF PREDNISONE AND PREDNISOLONE ON THYROID FUNCTION, WITH SPECIAL REFERENCE TO THYROXINE-BINDING PROTEIN IN NEPHROSIS

Abstract
Activation of the adrenal cortex by corticotropin and the administration of adrenal steroid hormones profoundly influences thyroid activity (1–4), the level of circulating thyroid hormone (5–7), and the renal clearance of iodine by the kidney (8–10). This paper is concerned with the results of experiments designed to demonstrate and elucidate the mechanisms whereby prednisone and prednisolone influence thyroid activity in man.