The antibiotic activity of prodigiosins against certain blue-green and green algae

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Abstract
The antibiotic activity of chemically separated fractions of prodigiosin, a pigment from the bacterium, Serratia marcescens, was tested on populations of Coelastrum microporum, Bracteacoccus cinnabarinus, Anacystis nidulans and Anabaena cylindrica. Test protocol involved the disk diffusion method of Barry. Zones of inhibition around the pigment saturated disks were measured and recorded. Blue-green algae are closely related to bacteria. It seems likely that prodigiosin factors (from amended and unamended media) act in a similar way against both groups of microorganisms. Blue green algae and bacteria show greater susceptibility to prodigiosin pigments than do the green algae. The antibiotic activity of prodigiosin against a broad spectrum of microorganisms is noteworthy. An irgasan-modified medium further enhances the antibiocity of prodigiosin against blue-green and green algae.

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