Spoligotype Signatures in the Mycobacterium tuberculosis Complex
- 1 January 2007
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 45 (1) , 237-240
- https://doi.org/10.1128/jcm.01429-06
Abstract
Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS 6110- defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity in drug and vaccine trials.Keywords
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