Controlled-Release Multiple-Units and Single-Unit Doses a Literature Review
- 1 January 1978
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 4 (1) , 53-67
- https://doi.org/10.3109/03639047809055639
Abstract
The strong influence exerted by the greatly varying normal gastrointestinal functions on the therapeutic value of a controlled-release single-unit dose is elucidated by a review of the literature. In this setting, the multiple-units dose comprising hundreds of mini-depots presents a highly preferable alternative which is due to a greater predictability and reproducibility of its therapeutic effect as well as a lowered risk of side effects.This publication has 36 references indexed in Scilit:
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