Inositol trisphosphate‐mediated Ca2+ release in beet mu;somes is inhibited by heparin
- 15 January 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 260 (1) , 70-72
- https://doi.org/10.1016/0014-5793(90)80068-t
Abstract
Microsomes from the storage root of red beet exhibit ATP‐dependent, protonophore‐sensitive Ca2+ accumulation, characteristic of the vacuolar membrane (tonoplast). A portion (20%) of this intravesicular Ca2+ store is specifically released by inositol 1,4,5‐trisphosphate (InsP3) with a K 0.5 = 0.54 μM. InsP3,‐mediated Ca2+ release is eliminated by low concentrations of heparin (K 0.5 = 86 nM). This result highlights the conservation between the animal and plant inositol 1,4,5‐trisphosphate‐mediated Ca2+ release mechanisms, despite the fact that they are located at different intracellular membranes.Keywords
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