Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes
Open Access
- 1 January 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 13 (2) , 617-630
- https://doi.org/10.1093/nar/13.2.617
Abstract
Mouse contains two functional, but differentially expressed, cytochrome c genes. One of these genes is expressed in all somatic tissues so far examined. The other gene is expressed only in testis and is assumed to be spermatogenesis-specific. The nucleotide sequence of four mouse cytochrome c-like genes has been determined, One of these genes (MC1) contains an intron and encodes a polypeptide sequence identical to the publIshed mouse somatic cytochrome c amino acid sequence. The other three genes can not properly encode a mouse cvtochrome c protein and appear to be pseudogenes which have arisen via an insertion into the mouse genome of a cDNA copy of a cytochrome c mRNA molecule.Keywords
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