Sensitivity of drosophila melanogaster to low concentrations of the gaseous 1, 2‐dibromoethane: I. Acute exposures

1 January 1979

journal article
Published by Wiley in Environmental Mutagenesis

Vol. 1 (1) , 15-18
https://doi.org/10.1002/em.2860010107

Abstract

Drosophila melanogaster males were exposed to gaseous 1, 2‐dibromoethane at concentrations lower than those used in aerosol treatments of suspected mutagens by other investigators. Premeiotic stages appear to be more sensitive than postmeiotic stages to gaseous mutagens. At an exposure of 125 ppm.hr, significant numbers of mutations were induced in spermatids, spermatocytes, and spermatogonia. Since this exposure increased the mutation rate in spermatogonial stages by a factor of 20–40 over the spontaneous rate, it appears that the lowest detectable exposures may be much lower than 125 ppm.hr for 1, 2‐dibromoethane.

Keywords

This publication has 6 references indexed in Scilit:

CHEMICAL INDUCTION OF MUTATIONS
Hereditas, 2010
Tables for determining the statistical significance of mutation frequencies
Published by Elsevier ,2003
Vinyl chloride mutagenesis in Drosophila melanogaster
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1977
Comparison of somatic mutation rates induced in tradescantia by chemical and physical mutagens
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1974
Mutation studies with Drosophila melanogaster exposed to four fluorinated hydrocarbon gases
Environmental Research, 1974
Mutagenicity testing of cyclamate and some pesticides inDrosophila melanogaster
Cellular and Molecular Life Sciences, 1974