Comparison of Antimouse and Antihorse Antibody Production during the Treatment of Allograft Rejection with OKT3 or Antithymocyte Globulin
- 1 January 1987
- journal article
- clinical trial
- Published by S. Karger AG in Nephron
- Vol. 46 (1) , 48-51
- https://doi.org/10.1159/000184434
Abstract
Antimouse antibody is produced from 40 to 68% of the time after administration of Orthoclone OKT3. In patients treated with OKT3, however, if the concomitant immunosuppression is not decreased, the incidence of the antibody production is reduced to 40%. Similarly, 33% of patients developed antihorse antibody after the initial antithymocyte globulin (ATG) administration. Most of the time, the antibody production is low-titered for both OKT3 and ATG.Keywords
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