Perkin communications. Synthesis of 3-amino-4-phenylpyridines: a novel strategy for the preparation ofCDring models of streptonigrin
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 9,p. 2611-2612
- https://doi.org/10.1039/p19900002611
Abstract
An efficient synthesis of 3-amino-4-phenylpyridine derivatives is reported. 3-Pivaloylaminopyridines were lithiated by butyl-lithium before reaction with iodine as electrophile to afford 4-iodo-3-pivaloylaminopyridines. Cross-coupling of the latter with suitable phenylboronic acids gives CD ring models of streptonigrin.This publication has 13 references indexed in Scilit:
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