Rectal and colonic ulceration in Behçet's disease

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Abstract
Two patients with Behçet's disease and involvement of the gastro-intestinal tract are described. One patient presented with rectal bleeding and perianal pain, and later developed peritonitis due to perforation of the sigmoid colon. The second patient developed rectal bleeding 4 years after the diagnosis of Behçt's disease, and examination showed this to be due to an ulcer in the anal canal. Behçet's disease should be considered as a possibility, albeit rare, in the differential diagnosis of rectal and colonic ulceration.