From Discrete Protein Kinetics to Continuous Brownian Dynamics: A New Perspective

Preprint

20 April 2001

preprint
Published by arXiv in arXiv

https://doi.org/10.48550/arXiv.physics/0104065

Abstract

An analysis on the discrete versus continuous views of kinetics of macromolecules is presented. It is shown that the discrete approach traditional to biochemistry is insufficient for understanding the dynamics of protein molecules in aqueous solution. A continous view based on the Brownian dynamics in energy landscape offers a more comprehensive description of the biological macromolecules. Two examples, one on protein folding and one on channel gating, are discussed.

Keywords

CONTINUOUS BROWNIAN
BROWNIAN DYNAMICS
PROTEIN KINETICS
DISCRETE PROTEIN
NEW PERSPECTIVE

All Related Versions

Version 1, 2001-04-20, ArXiv

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