Responses to Colchicine Therapeutic Trial in Rheumatoid Arthritis

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Abstract
IMPROVEMENT from colchicine therapy in patients with arthritic symptoms has always been accepted as indicative of gout.1 2 3 Other arthritides supposedly have not responded satisfactorily to this medication. A diagnostic test designated as the colchicine therapeutic trial has consequently been employed to differentiate gout from other rheumatic diseases. The colchicine therapeutic trial consists of administration of colchicine orally in doses of 0.6 mg. (1/100 gr.) every hour or every two hours until improvement ensues or until gastrointestinal complaints necessitate curtailment of the drug. If improvement results, the diagnosis is considered to be gout.This test has had an important role in . . .

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