The Family Approach to the Resolution of Racemates
- 18 September 1998
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 37 (17) , 2349-2354
- https://doi.org/10.1002/(sici)1521-3773(19980918)37:17<2349::aid-anie2349>3.0.co;2-i
Abstract
The resolution of racemates is revolutionized with the method presented here, in which mixtures (“families”) of structurally and stereochemically related resolving agents are used to precipitate salts of acidic or basic racemates rapidly and dependably. The racemate is usually separated in a single operation into enantiomers—the enantiomeric excesses and yields are good to excellent. Reagent mixtures with racemic or achiral components have also been developed.This publication has 0 references indexed in Scilit: