ALIPHATIC DIAMINES AND HISTAMINE IN SERUM OF PATIENTS WITH RHEUMATOID-ARTHRITIS

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 37  (9-10) , 329-334
Abstract
The concentration of histamine, cadaverine, putrescine spermidine and spermine was measured in blood serum of patients with rheumatoid arthritis (RA). In comparison to normals there is no satistically significant difference in the concentration of putrescine and spermidine in blood serum of RA patients. Spermine which also could be detected in all samples did not show distinct abnormalities from healthy subjects. Histamine and cadaverine in measurable amounts were only in particular cases. A relation between increased histamine and basophil count was not demonstrable. There is apparently no correlation between histidinemia which is reported in the literature of RA patients in blood serum and plasma, and histamine production in the blood.