SMALL-BOWEL ULCERATION IN PATIENTS RECEIVING NONSTEROIDAL ANTIINFLAMMATORY DRUGS FOR RHEUMATOID-ARTHRITIS
- 1 January 1986
- journal article
- research article
- Vol. 58 (225) , 53-58
Abstract
Evidence is presented for a non-specific ulcerative process in the small bowel of patients with rheumatoid arthritis. All three cases presented with lower gastrointestinal bleeding; on withdrawal of non-steroidal anti-inflammatory drugs no further bleeding occurred. Non-steroidal anti-inflammatory drugs may lead to small bowel ulceration in inhibiting mucosal glycoprotein synthesis and increasing intestinal permeability.This publication has 8 references indexed in Scilit:
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