Conversion of17O/18O-labelled δ-(L-α-aminoadipyl)–L-cycteinyl–D-valine into17O/18O-labelled isopenicillin N in a cell-free extract of C. acremonium
- 1 January 1982
- journal article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 2,p. 137-139
- https://doi.org/10.1039/c39820000137
Abstract
δ-(L-α-Amino[1,1,6-17O/18O]-adipyl)-L-cysteiny-D-valine was converted into isopenicillin N in cell-free extracts of Cephalosporium acremonium with no loss of 17O/18O label as shown by 17O n.m.r. spectroscopy and mass spectrometry; incubation of unlabelled tripeptide in cell-free system containing 17O/18O-enriched water produced isopenicillin N with no incorporation of 17O/18O.Keywords
This publication has 0 references indexed in Scilit: