Variability in the response of different male subjects to the effect of marathon running on the increase in plasma high density lipoprotein

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Abstract
The acute effects of running a 42.2 km marathon race on the concentration and composition of the plasma lipoproteins were studied in 56 men of varying fitness, training experience, age and physical characteristics. There was no change in the mean concentration of total serum cholesterol, but a 10.9% increase (PPPPPn=13) had a significantly greater (P4 h; n=14). The observed alterations in the lipoproteins are consistent with increased rates of lipolysis of triacylglycerol-rich lipoproteins and of cholesterol esterification during the marathon and suggest that the effect of exercise on the activities of the enzymes that catalyse these processes may vary considerably between different subjects and may be modulated by training and other factors.

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