Autonomic Control and Vascular Changes during Penile Erection in Monkeys

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Abstract
The mean pressure in the unstimulated corpus cavernosum of monkeys was 12.1 mm Hg. Pelvic nerve stimulation at 8 to 10 Hz produced penile extension and the mean pressure increased to 64.3 mm Hg (47-84% of carotid artery pressure) after a latency of 10 s. On stopping stimulation, recovery to resting levels occurred within 2 min. The response was not blocked by atropine or propranolol. Blood flow through two 19 gauge needles inserted into the corpus cavernosum increased in parallel with the pressure changes, indicating that arterial inflow increased. Stimulation of either hypogastric nerves or the sympathetic chain produced penile retraction but increased corpus cavernosal pressure. The response to pelvic nerve stimulation was partially blocked. It was concluded that both of these nerves contract penile erectile tissue within the corpus cavernosum and constrict arterial inflow.