A Selected Review of Risk Models: One Hit, Multihit, Multistage, Probit, Weibull, and Pharmacokinetic
- 1 July 1985
- journal article
- review article
- Published by SAGE Publications in Journal of the American College of Toxicology
- Vol. 4 (4) , 271-278
- https://doi.org/10.3109/10915818509078679
Abstract
This paper provides some of the underlying mathematical derivations for the one-hit, multihit, multistage, Weibull, and pharmacokinetic risk models. Our purposes are to remove for the nonmathematician some of the mystery as to the derivation of the formulas for each particular risk model and to discuss some of the assumptions contained in the risk models. Confidence limits and maximum likelihood estimates of the model parameters are not discussed, since they are not pertinent to our objectives. Rai and Van Ryzin(1) have outlined these procedures in sufficient detail.Keywords
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