Localization of absorbers in scattering media by use of frequency-domain measurements of time-dependent photon migration
- 1 June 1994
- journal article
- Published by Optica Publishing Group in Applied Optics
- Vol. 33 (16) , 3562-3570
- https://doi.org/10.1364/ao.33.003562
Abstract
Frequency-domain studies of time-dependent light propagation in tissuelike phantoms that contain optical heterogeneities are described. Specifically the phase shift and amplitude modulation of reemergent light were measured when illuminated by an amplitude-modulated light source. Changes in the phase angle and the extent of modulation revealed the presence of a light-absorbing object. Furthermore the magnitude and direction of these changes were sensitive to the absorber depth and the light modulation frequency in a manner that could be used to infer the location of the heterogeneity. These data suggest the feasibility of optical imaging by frequency-domain methods.Keywords
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