AN UNUSUAL CASE OF WILSONS-DISEASE
- 1 January 1985
- journal article
- research article
- Vol. 55 (216) , 63-73
Abstract
A man of 61 with a 26-yr history of progressive cerebellar ataxia was admitted to the hospital. He had chronic liver disease and died 22 days after admission. A diagnosis of hepatolenticular degeneration (Wilson''s disease) was supported by clinical investigations and confirmed at autopsy, when tissue Cu studies were performed. Several unusual features were present, including a unilateral Kayser-Fleischer ring, a hepatocellular carcinoma, peripheral neuropathy, pontine demyelination and calcification of neurons in the medulla. The significance of these findings is discussed with a review of the relevant literature.This publication has 5 references indexed in Scilit:
- Late Onset of Wilson's DiseaseArchives of Neurology, 1981
- Pigmented Corneal Rings in Non-Wilsonian Liver DiseaseAnnals of Internal Medicine, 1977
- CERULOPLASMIN IN HEALTH AND DISEASE*Annals of the New York Academy of Sciences, 1961
- A FURTHER NOTE ON HEPATO-LENTICULAR DEGENERATIONBrain, 1926
- PROGRESSIVE LENTICULAR DEGENERATION: A FAMILIAL NERVOUS DISEASE ASSOCIATED WITH CIRRHOSIS OF THE LIVERBrain, 1912