Studies of Organic Catalytic Reactions. III. The Hydration Mechanism of Nitriles to Amides with Nickel Catalysts
- 1 January 1966
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 39 (1) , 8-14
- https://doi.org/10.1246/bcsj.39.8
Abstract
Benzonitrile, benzyl cyanide, acetonitrile and 2-cyanopyridine give the corresponding amides by the hydration with nickel catalysts and water. The effect of pyridine and thiophene on the hydration has been investigated. In general, the yield of amides increases upon the addition of a suitable amount of pyridine. On the contrary, the reaction is distinctly suppressed by the addition of thiophene. This fact is in striking contrast to the effect on the hydrogenation of nitriles. The correlation of the catalytic functions in hydration and the hydrogenation of nitriles has been studied, and the hydration mechanism with nickel catalysts has been discussed.This publication has 3 references indexed in Scilit:
- Studies on Organic Catalytic Reactions. II. The Hydration of Nitriles to Amides with Nickel CatalystsBulletin of the Chemical Society of Japan, 1964
- Catalytic Hydrogenation of Aromatic NitritesBulletin of the Chemical Society of Japan, 1959
- Über die Reduktion von aromatischen Nitro‐cyan‐verbindungenHelvetica Chimica Acta, 1925