The Effect of Luteinizing Hormone Releasing Hormone (LHRH) Antiserum Administrationon Gonadotropin Secretion in the Rhesus Monkey12
- 1 March 1977
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 100 (3) , 663-667
- https://doi.org/10.1210/endo-100-3-663
Abstract
Single i.v. injections of a rabbit antiserum to synthetic LHRH promptly suppressed serum LH [luteinizing hormone] and FSH [follicle-stimulating hormone] concentrations in ovariectomized rhesus monkeys [Macaca mulatta]. Gonadotropin levels remained depressed for 10-21 days, the approximate duration of enhanced LHRH binding activity in the circulation. Doses of LHRH antiserum sufficient to reduce tonic gonadotropin secretion did not modify the time course or magnitude of estrogen-induced gonadotropin surges. These negative findings cannot be interpreted to signify that such surges are not caused by a release of LHRH.This publication has 3 references indexed in Scilit:
- ERe-examination of Porcine and Bovine Hypothalamic Fractions for Additional Luteinizing Hormone and Follicle Stimulating Hormone-Releasing ActivitiesEndocrinology, 1976
- Periovulatory Progesterone Concentration in the Peripheral Plasma of the Rhesus Monkey with a Methodologic Note on the Detection of OvulationEndocrinology, 1968
- Levels of Progesterone in Peripheral Plasma During the Menstrual Cycle of the Rhesus MonkeyEndocrinology, 1967