Using Absolute and Relative Reasoning in the Prediction of the Potential Metabolism of Xenobiotics

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Abstract
To be useful, a system which predicts the metabolic fate of a chemical should predict the more likely metabolites rather than every possibility. Reasoning can be used to prioritize biotransformations, but a real biochemical domain is complex and cannot be fully defined in terms of the likelihood of events. This paper describes the combined use of two models for reasoning under uncertainty in a working system, METEORone model deals with absolute reasoning and the second with relative reasoning.